They are the primary storage option for cryopreservation, preserving lining cells and tissues at negative temperatures. The containers are vacuum insulated to reduce heat transfer and the vaporization rate of the products during transit. The cryotank has low heat conductivity, a high vacuum with high-performance construction, and advanced insulation materials to ensure high thermal efficiency.
Here are some factors to consider before purchasing a tank for any cryogenic product:
1. Quantity and Size of Shipment
The global cryogenic container market is segmented on region, end-user, and product.
The market classification includes cryo boxes, vials, cryotubes, and cryogenic supply tanks. As such, every product requires a different design depending on its quantity, size, and characteristics.
Large shipping cryogenic containers can hold 20,000 liters to 22,500 liters (for the 20-foot version) and approximately 46,000 liters for the 40-foot tank. Dewar flasks are portable and suitable for shipping smaller quantities.
2. Time to Transport
Every shipping cryogenic container has a given time to function efficiently. Before selecting a container, consider the time required for the shipment to reach its destination since there is a finite amount of resources to use. A large cryogenic tank can run continuously for up to 12 days, unlike the smaller versions that run for about seven days.
3. Type of Transportation
The method you intend to use when transporting the products also determines the right cryotank to buy. In the past, it was challenging to ship compressed gases by air, but now it is possible through cryogenic air cargo and specialized containers. The containers have a unique material that absorbs and saves liquid nitrogen, preventing an overflow during delivery.
4. GDP Compliance
Shipping cryogenic containers should uphold good distributor practices (GDP) and remain compliant with its regulations. While it is not a global requirement, the certification requires pharmaceutical product handlers to meet stringent WHO standards for safety and security. All pharmaceutical companies and logistic partners must comply with the regulations in the European Union or U.S. Food & Drug Administration.
5. Protective Shipping Carton
If you are shipping sensitive material through the air or by sea, you can add a protective carton, ensuring the biological samples remain at cryogenic temperature without damage. The positioning of the cryogenic container, especially for the Dewar flask, is crucial during shipping. Keep the container upright to improve the hold time. When they tilt sideways or upside down, the hold time significantly reduces, which is why you must ship the container upright without much shaking.
You can buy or rent when looking for shipping cryogenic containers. The Dewar flask is located at the bottom of the price list, ranging between €85 to €1,000, with the price changing based on size and extra features. The larger tanks range between €25,000 and €45,000 due to the storage capacity of between 3,160 liters to 61,620 liters. You can also rent the devices to keep costs down if you will not be sending shipments long term.